Hypothyroidism
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Hypothyroidism is the disease state in humans
and other animals caused by insufficient production of thyroid
hormone by the thyroid gland. Cretinism is a form of hypothyroidism
found in infants.
There are many side effects of a sluggish
thyroid gland and the resulting slower metabolism.
- First of all
it
effects your energy level greatly, and with a slower
metabolism and subsequent reduction in activity (and energy)
- there is
often unwanted weight gain.
- Unfortunately, a person's
health is effected, as well.
Causes of Hypothyroidism
About three percent of the general population
is hypothyroid.[1] Factors such as iodine deficiency or exposure
to Iodine-131 (I-131) can increase that risk. There are a
number of causes for hypothyroidism. Historically, and still
in many developing countries, iodine deficiency is the most
common cause of hypothyroidism worldwide. In iodine-replete
individuals, hypothyroidism is mostly caused by Hashimoto's
thyroiditis, or by a lack of the thyroid gland or a deficiency
of hormones from either the hypothalamus or the pituitary.
Hypothyroidism can result from postpartum thyroiditis, a
condition that affects about 5% of all women within a year
after giving birth. The first phase is typically hyperthyroidism.
Then, the thyroid either returns to normal or a woman develops
hypothyroidism. Of those women who experience hypothyroidism
associated with postpartum thyroiditis, one in five will
develop permanent hypothyroidism requiring life-long treatment.
Hypothyroidism can also result from sporadic inheritance,
sometimes autosomal recessive.
Hypothyroidism is also a relatively common hormone disease
in domestic dogs, with some specific breeds having a definite
predisposition.[2]
Temporary hypothyroidism can be due to the Wolff-Chaikoff
effect. A very high intake of iodine can be used to temporarily
treat hypothyroidism, especially in an emergency situation.
Although iodine is substrate for thyroid hormones, high levels
prompt the thyroid gland to take in less of the iodine that
is eaten, reducing hormone production.
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